Diquafosol sodium ophthalmic solution for the treatment of dry eye: clinical evaluation and biochemical analysis of tear composition

Shigeyasu Chika; Yamada Masakazu; Akune Yoko; Tsubota Kazuo

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Diquafosol sodium ophthalmic solution for the treatment of dry eye: clinical evaluation and biochemical analysis of tear composition

机译：Diquafosol钠眼药水治疗干眼症：眼泪成分的临床评估和生化分析

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摘要

To evaluate the clinical efficacy of 3 % diquafosol sodium ophthalmic solution for dry eye, and to analyze the concentration of tear proteins and mucin-like substances after the treatment.

机译：评估3％的地夸磷索钠眼用溶液对干眼症的临床疗效，并分析治疗后眼泪蛋白和粘蛋白样物质的浓度。

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来源
《Japanese Journal of Ophthalmology》 |2015年第6期|共6页
作者
Shigeyasu Chika; Yamada Masakazu; Akune Yoko; Tsubota Kazuo;
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原文格式 PDF
正文语种 eng
中图分类眼科学;
关键词
Diquafosol ophthalmic solution; Dry eye syndrome; Mucins; Tears; Sialic acid;

机译：地夸磷索滴眼液;干眼症;粘胶;眼泪;唾液酸;

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专利

1. Diquafosol sodium ophthalmic solution for the treatment of dry eye: clinical evaluation and biochemical analysis of tear composition [J] . Shigeyasu Chika, Yamada Masakazu, Akune Yoko, Japanese Journal of Ophthalmology . 2015,第6期

机译：Diquafosol钠眼药水治疗干眼症：眼泪成分的临床评估和生化分析
2. Efficacy and Safety of Topical 3% Diquafosol Ophthalmic Solution for the Treatment of Multifactorial Dry Eye Disease: Meta-Analysis of Randomized Clinical Trials [J] . Nam Kiyeun, Kim Hyun Jung, Yoo Aeri Ophthalmic Research: Journal for Research in Experimental and Clinical Ophthalmology . 2019,第4期

机译：局部3％毒药眼科溶液治疗多因其干眼症的疗效和安全性：随机临床试验的荟萃分析
3. Tear volume estimation using a modified Schirmer test: a randomized, multicenter, double-blind trial comparing 3% diquafosol ophthalmic solution and artificial tears in dry eye patients [J] . Hideki Miyake, Yuri Kawano, Hiroshi Tanaka, Clinical ophthalmology . 2016,第3期

机译：使用改良的Schirmer检验估算泪液量：一项随机，多中心，双盲试验，比较了干眼症患者中3％的Diquafosol眼药水和人工泪液
4. HL036337 Ophthalmic Solution: Topical TNF Blocker for Dry Eye Disease [C] . Minjae Shin PEGS . 2015

机译：HL036337眼科溶液：用于干眼症的局部TNF阻滞剂
5. The Development of a Validated Clinically Meaningful Endpoint for the Evaluation of Tear Film Stability as a Measure of Ocular Surface Protection for Use in the Diagnosis and Evaluation of Dry Eye Disease. [D] . Abelson, Richard. 2012

机译：开发用于泪膜稳定性评估的临床上有意义的终点，作为眼表保护措施，用于干眼病的诊断和评估。
6. Tear volume estimation using a modified Schirmer test: a randomized multicenter double-blind trial comparing 3 diquafosol ophthalmic solution and artificial tears in dry eye patients [O] . Hideki Miyake, Yuri Kawano, Hiroshi Tanaka, 2016

机译：使用改良的Schirmer检验估算泪液量：一项随机多中心双盲试验比较了干眼患者中3％的Diquafosol眼药水和人工泪液
7. Efficacy and Safety of Topical 3 Diquafosol Ophthalmic Solution for the Treatment of Multifactorial Dry Eye Disease: Meta-Analysis of Randomized Clinical Trials [O] . Kiyeun Nam, Hyun Jung Kim, Aeri Yoo 2019

机译：局部3％Diquafosol眼科溶液治疗多因其干眼症的疗效和安全性：随机临床试验的Meta分析

Diquafosol sodium ophthalmic solution for the treatment of dry eye: clinical evaluation and biochemical analysis of tear composition

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