PRENYLATED FLAVONOIDS FROM TEPHROSIA APOLLINEA

摘要

Re-investigation of the chloroform extract of the aerial part of Tephrosia apollinea afforded seven new 8-prenylated flavonoids namely tephroapollin A-G (1-7).The structures were established by spectroscopic methods,including HR-CI-MS,~1H,~(13)C,DEPT,HMQC,HMBC and ROESY experiments.The relative configuration analysis of stereocenters for 5-7 was carried out on the basis of the reported J-based method.General toxicity of the isolated compounds was determined by brine shrimp lethality bioassay.