RELATIVE STABILITIES OF 1- AND 2-SUBSTITUTED 1,2,3-TRIAZOLES

摘要

N-(a-Aminoalkyl)-1,2,3-triazoles are potentially tautomeric between the 1- and 2-substituted forms. They exist in solution predominantly as 2-isomers as shown by ~1H and ~(13)C NMR; electron attracting substituents on the amino nitrogen increase the proportion of the 1-isomer in the equilibrium mixture.