CONVENIENT SYNTHESIS OF NOVEL NITRONES: (Z)-4-AMINO-5- (HYDROXYIMINO)-2,5-DIHYDRO-1H-IMIDAZOLE3-OXIDES

摘要

Highly functionalized derivatives of (Z)-4-amino-5-(hydroxyimino)-2,5-dihydro-1H-imidazole 3-oxide were first and conveniently synthesized by the reactions of 3,4-diaminoglyoxime with benzaldehyde derivatives in the presence of p-toluenesulfonic acid. The procedure represents an effective method to obtain a new kind of nitrones.