SYNTHESIS OF 3a-(INDOL-3-YL)-1,2,3,3a,8,8a-HEXAHYDROPYRROLO[2,3-b]INDOLE CORE OF LEPTOSINS D-F BASED ON NUCLEOPHILIC SUBSTITUTION REACTION ON INDOLE NUCLEUS~1

摘要

A simple and convenient synthetic methodology for 3a-(indo-3-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole, the core structure of leptosins D-F is developed by applying nucleophilic substitution reaction of 1-hydroxytryptamines.