convenient diversification of pyrrolo [2,3-b]-quinolines by iodonation and palladium-catalyzed coupling reactions

摘要

The 2-trimemylsilylpyrrolo[2,3-b]qumolines were easily transformed into 2-iodopyrrolo[2,3-b]quinolines under NIS/CH_3CN. The palladium-catalyzed Heck, Stille, and Suzuki coupling reactions of 2-iodo[2,3-b]quinolines provided diverse 1,2,3-trisubstituted pyrrolo[2,3-b]quinolines in moderate to high yields.