Electrolytic partial fluorination of organic compounds. 66. anodic fluorination of (thiazol-2-yl) acetonitriles

摘要

Electrochemical partial fluorination of (4-arylthiazol-2-yl) acetonitriles was carried out to afford the corresponding (4-aryl-5-fluoro-5H-thiazol-2-ylidene) acetonitriles as main products in addition to (4-aryl-5-fluorothiazol-2-yl) acetonitriles and (4-arylthiazol-2-yl) fluoroacetonitriles. AM1 calculations were conducted to compare the stability of the fluorinated products.