BISMUTH TRIFLATE-CHIRAL BIPYRIDINE COMPLEX CATALYZED ASYMMETRIC RING OPENING REACTIONS OF MESO-EPOXIDE IN WATER

摘要

Catalytic asymmetric ring-opening reactions of meso-epoxides with aromatic amines have been explored.The reactions proceeded in the presence of a catalytic amount of bismuth triflate (Bi(OTf)_3),chiral bipyridine ligand (1) and sodium dodecylbenzene sulfonate (SDBS) in pure water to give the corresponding beta-amino alcohols in good yields with high enantioselectivities.