Anticoccidial activity of some azacyclo organoborinates

摘要

A series of new azacyclo organoborinates derivatives of piperidinyl and pyridinyl alcohols with anticoccidial activity in vivo assay system in battery trials are described. Parameters of anticoccidial efficacy that were evaluated were today weight, lesion scores and number of oocysts. Among them, di (4-chloro-phenyl)(2-piperidynylmethoxy-O,N) boron, and di (3-trifluoromethyl-phenyl)(2-pyridinylethoxy-O,N) boron showed good anticoccidial activity against both of the important parasite, Eimeria tenella and Eimeria acervulina.