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首页> 外文期刊>JAMA internal medicine >Correlates of repeat lipid testing in patients with coronary heart disease
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Correlates of repeat lipid testing in patients with coronary heart disease

机译:冠心病患者重复血脂检测的相关性

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IMPORTANCE Understanding the frequency and correlates of redundant lipid testing could identify areas for quality improvement initiatives aimed at improving the efficiency of cholesterol care in patients with coronary heart disease (CHD). OBJECTIVE To determine the frequency and correlates of repeat lipid testing in patients with CHD who attained low-density lipoprotein cholesterol (LDL-C) goals and received no treatment intensification. DESIGN, SETTING, AND PARTICIPANTS We assessed the proportion of patients with LDL-C levels of less than 100 mg/dL and no intensification of lipid-lowering therapy who underwent repeat lipid testing during an 11-month follow-up period.We performed logistic regression analyses to evaluate facility, provider, and patient characteristics associated with repeat testing. In total, we analyzed 35 191 patients with CHD in a Veterans Affairs network of 7 medical centers with associated community-based outpatient clinics. MAIN OUTCOMES AND MEASURES Frequency and correlates of repeat lipid testing in patients having CHD with LDL-C levels of less than 100 mg/dL and no further treatment intensification with lipid-lowering therapies. RESULTS Of 27 947 patients with LDL-C levels of less than 100 mg/dL, 9200 (32.9%) had additional lipid assessments without treatment intensification during the following 11 months (12 686 total additional panels; mean, 1.38 additional panel per patient). Adjusting for facility-level clustering, patients with a history of diabetes mellitus (odds ratio [OR], 1.16; 95% CI, 1.10-1.22), a history of hypertension (OR, 1.21; 95%CI, 1.13-1.30), higher illness burden (OR, 1.39; 95%CI, 1.23-1.57), and more frequent primary care visits (OR, 1.32; 95%CI, 1.25-1.39) were more likely to undergo repeat testing, whereas patients receiving care at a teaching facility (OR, 0.74; 95%CI, 0.69-0.80) or from a physician provider (OR, 0.93; 95%CI, 0.88-0.98) and those with a medication possession ratio of 0.8 or higher (OR, 0.75; 95%CI, 0.71-0.80) were less likely to undergo repeat testing. Among 13 114 patients who met the optional LDL-C target level of less than 70 mg/dL, repeat lipid testing was performed in 8177 (62.4%of those with LDL-C levels of <70 mg/dL) during 11 follow-up months. CONCLUSIONS AND RELEVANCE One-third of patients having CHD with LDL-C levels at goal underwent repeat lipid panels. Our results highlight areas for quality improvement initiatives to reduce redundant lipid testing. These efforts would be more important if the forthcoming cholesterol guidelines adopt a medication dose-based approach in place of the current treat-to-target approach.
机译:重要说明了解冗余脂质测试的频率和相关性可以确定质量改进计划的领域,这些计划旨在提高冠心病(CHD)患者的胆固醇治疗效率。目的确定达到低密度脂蛋白胆固醇(LDL-C)目标且未接受强化治疗的冠心病患者重复进行脂质测试的频率及其相关性。设计,地点和参与者我们评估了LDL-C水平低于100 mg / dL且未进行降脂治疗的患者的比例,这些患者在11个月的随访期间进行了重复的脂质测试。进行回归分析以评估与重复测试相关的设施,提供者和患者特征。我们总共在7个医疗中心的退伍军人事务网络中对35191例冠心病患者进行了分析,并拥有相关的社区门诊诊所。主要结果和措施患有低密度脂蛋白胆固醇低于100毫克/分升且无进一步降脂治疗的冠心病患者的重复脂质测试频率和相关性。结果在27 947名LDL-C水平低于100 mg / dL的患者中,有9200名(32.9%)在接下来的11个月中进行了额外的血脂评估,而未进行任何治疗强化治疗(总共增加了12686小组;每位患者平均增加了1.38小组) 。调整设施级聚类后,有糖尿病史(赔率[OR]为1.16; 95%CI为1.10-1.22),高血压病史(OR为1.21; 95%CI为1.13-1.30)的患者,较高的疾病负担(OR,1.39; 95%CI,1.23-1.57)和更频繁的初级保健就诊(OR,1.32; 95%CI,1.25-1.39)更有可能接受重复测试,而在教学设施(OR,0.74; 95%CI,0.69-0.80)或来自医师提供者(OR,0.93; 95%CI,0.88-0.98)以及拥有药物比率为0.8或更高(OR,0.75; 95)的机构%CI,0.71-0.80)不太可能进行重复测试。在13 114名达到可选的LDL-C目标水平低于70 mg / dL的患者中,在11次随访中,对8177名患者进行了重复脂质测试(占LDL-C水平<70 mg / dL者中的62.4%)。个月。结论和相关性患有低密度脂蛋白胆固醇水平达到目标的冠心病患者中有三分之一接受了重复性脂质检查。我们的结果突出了质量改进计划的领域,以减少多余的脂质测试。如果即将出台的胆固醇指南采用基于药物剂量的方法来代替当前的“以治疗为目标”的方法,那么这些努力将更加重要。

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