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Carotid artery stenting before cardiac surgery: A promising path down a muddy road?

机译:心脏手术前的颈动脉支架置入术:一条泥泞道路上的前途吗?

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摘要

The management of synchronous carotid disease and coronary or valvular disease requiring surgical repair has been a constant challenge to clinicians for decades and for a variety of reasons. First, although it is a vexing problem, it is relatively infrequent, such that any single institution/ operator experience in management will always be clouded by "the last case I did" syndrome, more reflective than definitive. Second, even in patients without carotid stenosis, the risk of stroke inherent in cardiac surgery from other sources (atheroembolic from aortic manipulation, air em-boli, and so on) clouds the assessment of the neurological "natural" history of the unoperated carotid stenosis in this setting. However, it seems clear enough that the patient with symptomatic carotid disease is at most risk and requires further management consideration, but that most asymptomatic patients with unilateral disease can withstand a cardiac operation with little increase in overall stroke risk and, therefore, should not be subjected to carotid revascu-larization risks (2). Next, the published database that generally helps guide such decisions in practice comprises largely single-center reports, and usually retrospectively analyzed. A recent Cochrane attempt to review all the published randomized data on the subject could not be completed, because there were no such studies in existence (3).
机译:几十年来,由于各种原因,需要手术修复的同时颈动脉疾病和冠状动脉或瓣膜疾病的管理一直是临床医生面临的持续挑战。首先,尽管这是一个令人烦恼的问题,但却相对很少见,因此,任何单个机构/运营商在管理方面的经验都将始终被“我做的最后一件事”综合症所笼罩,而不是确定性的。第二,即使在没有颈动脉狭窄的患者中,心脏外科手术固有的其他来源的中风风险(来自主动脉操作,空气肺动脉栓塞等引起的动脉粥样硬化)也覆盖了未经手术的颈动脉狭窄的神经系统“自然”病史的评估在这种情况下。但是,似乎足够清楚的是,有症状的颈动脉疾病的患者风险最高,需要进一步的管理考虑,但是大多数无症状的单侧疾病的患者可以承受心脏手术,但总体中风风险增加不大,因此,不应遭受颈动脉再血管化风险(2)。接下来,通常在实践中有助于指导此类决策的已发布数据库主要包括单中心报告,并且通常进行回顾性分析。 Cochrane最近尝试复习有关该主题的所有随机数据的尝试均无法完成,因为目前尚无此类研究(3)。

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