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首页> 外文期刊>Developmental Medicine and Child Neurology >Prophylactic femoral varization osteotomy for contralateral stable hips in non-ambulant individuals with cerebral palsy undergoing hip surgery: Decision analysis
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Prophylactic femoral varization osteotomy for contralateral stable hips in non-ambulant individuals with cerebral palsy undergoing hip surgery: Decision analysis

机译:预防性股骨静脉曲张截骨术对非救治性脑瘫患者进行对侧稳定髋关节手术的决策分析

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Aim This study was undertaken to determine the need for concurrent prophylactic femoral varization osteotomy (FVO) of contralateral stable hips at the time of hip reconstructive surgery on unstable hips in non-ambulant individuals with cerebral palsy (Gross Motor Function Classification System levels IV and V). Method A decision analysis model was constructed that included (1) the probability of unstable hips during observation of the contralateral stable hips, (2) unstable hip rate (subluxation or dislocation rate) after prophylactic FVO or after delayed reconstructive surgery (including FVO) for unstable hips, and (3) complication rates after concurrent prophylactic FVO or after hip reconstructive surgery. The final outcome score was based on pain utility measures. The probabilities of all cases and the utility score were obtained by literature review. Results The decision model favoured concurrent prophylactic FVO for the contralateral stable hips over observation (pain utility measure scores 0.814 vs 0.781). In a one-way sensitivity analysis, the decision model favoured concurrent prophylactic FVO when the unstable hip rate of contralateral stable hips during observation was 27% or over. Concurrent prophylactic surgery also demonstrated higher utility scores than observation when the unstable hip rate after FVO was between 0% and 29%. Interpretation The decision analysis model demonstrated that concurrent prophylactic FVO for a contralateral stable hip in individuals with cerebral palsy undergoing hip reconstructive surgery was beneficial from a medical perspective, which was based on current evidence.
机译:目的进行本研究以确定在非救治性脑瘫患者中,对不稳定的髋关节进行髋关节重建手术时,对侧稳定髋关节同时进行预防性股骨静脉曲张截骨术(FVO)的必要性(总运动功能分类系统IV级和V级)。方法建立决策分析模型,其中包括(1)观察对侧稳定髋关节时髋关节不稳定的可能性,(2)预防性FVO或延迟重建手术(包括FVO)后的不稳定髋关节发生率(半脱位或脱位率)。髋关节不稳定,以及(3)并发预防性FVO或髋关节重建手术后的并发症发生率。最终结果评分基于疼痛效用度量。所有文献的概率和效用得分均通过文献综述获得。结果决策模型偏向于对侧稳定髋关节并发预防性FVO优于观察(疼痛效用评分分别为0.814和0.781)。在单向敏感性分析中,当观察期间对侧稳定髋关节的不稳定髋部率为27%或更高时,决策模型倾向于同时进行预防性FVO。当FVO后不稳定髋部发生率在0%至29%之间时,并发预防性手术的效用得分也高于观察结果。解释决策分析模型表明,从医学的角度出发,基于当前证据,并发预防性FVO对接受了髋关节重建手术的脑瘫患者的对侧稳定髋关节有益。

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