Precis Children's toys with metal components are potential sources of nickel exposure in young children. Awareness and avoidance of such toys may help prevent allergic contact dermatitis from nickel. Discussion Early age at exposure is a well-recognized risk factor for developing nickel allergy. In our patch-tested population of US children between 2001 and 2006, we found clinically relevant nickel sensitization in 17% of patients younger than 18 years. This rate has remained constant in our latest data (unpublished). One aspect we did not speak of previously was the number of patients' parents, trained with a dimethylglyoxime (DMG) test in hand, who found nickel in their children's toys.
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