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Treatment of surgical scars using a 595-nm pulsed dye laser using purpuric and nonpurpuric parameters: A comparative study

机译:使用紫和非紫参数的595 nm脉冲染料激光治疗手术疤痕的比较研究

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Background Many studies have examined laser treatment of scars, but cosmetic results have been variable. Although no studies have examined the effect of purpura on scar improvement using the pulsed dye laser (PDL), many clinicians believe inducing purpura results in better and quicker improvement. Objective To determine whether PDL treatment of fresh surgical scars with purpura-inducing settings improves clinical appearance more than non-purpura-inducing settings or no treatment. Methods Twenty-six subjects with surgical scars enrolled in this prospective study. Scars were divided into three equal segments; treatment was randomized: 595-nm PDL with purpuric (1.5 ms) or nonpurpuric (10 ms) settings or no treatment. Fluences were adjusted to Fitzpatrick skin type. Scars were treated three times, 1 month apart, beginning at suture removal. Outcome measures included Vancouver Scar Scale (VSS) and blind clinical ratings. Results The nonpurpuric condition showed significant improvement on the VSS total score, vascularity, and pliability ratings. The purpuric condition demonstrated a trend for improvement on the VSS total. According to blind observer ratings, all conditions improved, without differences between groups. Conclusion Nonpurpuric settings on the PDL resulted in significant improvements in the appearance of fresh surgical scars for vascularity, pliability, and VSS total scores, although all scar segments improved over time.
机译:背景技术许多研究已经检查了激光对疤痕的治疗方法,但美容效果却各不相同。尽管没有研究使用脉冲染料激光(PDL)研究紫癜对疤痕改善的作用,但许多临床医生认为,诱发紫癜会导致更好,更快的改善。目的确定PDL治疗是否引起紫癜的新鲜手术疤痕比非诱发紫癜的治疗或不治疗能改善临床外观。方法这项前瞻性研究纳入了26例手术疤痕患者。疤痕被分为三个相等的部分。治疗是随机的:采用紫癜(1.5 ms)或非紫癜(10 ms)设置或不进行治疗的595 nm PDL。调整通量以适应Fitzpatrick的皮肤类型。从去除缝线开始,对疤痕进行了3次治疗,相隔1个月。结果指标包括温哥华疤痕量表(VSS)和盲目临床评分。结果非紫癜状态对VSS总评分,血管性和柔韧性评分有显着改善。紫癜状态显示VSS总水平有改善的趋势。根据盲人观察者的评分,所有情况都得到了改善,两组之间没有差异。结论PDL的非紫癜设置可显着改善新鲜手术疤痕的外观,从而改善血管,柔韧性和VSS总分,尽管随着时间的推移所有疤痕部位均得到改善。

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