Two new taxane-glycosides from the needles of Taxus canadensis

摘要

Two minor taxane glycosides were isolated for the first time from the needles of Taxus canadensis. Their structures were characterized as 2 alpha,5 alpha-diacetoxy-10 beta-(6'-O-acetyl-beta-D-glucopyranosyl)oxy-14 beta-[(2'R,3'S)3'-hydroxy-2'-methylbutanoyl] oxytaxa-4(20),11-diene (1) and 2 alpha, 14 beta-diacetoxy-10 beta-(beta-D-glucopyranosyl)oxytaxa-4(20),11-dien-5 beta-ol (2) on the basis of 1D and 2D NMR data analysis and confirmed by high-resolution fast atom bombardment mass spectrometry.