Evaluation of toxic effects of lambdacyhalothi in on the haematology and selected biochemical parameters of African catfish Clarias gariepinus

摘要

The potential acute and chronic toxic effects of lambdacyhalothrin (LCT) on African catfish Clarias gariepinus were evaluated. Lethal concentrations (LC) were determined using 0.2, 0.3, 0.4, 0.5 and 0.6 ppm of LCT. Haematological and biochemical parameters were evaluated on fish treated with 0.001, 0.005, 0.010 and 0.025 ppm of LCT. Blood samples were collected on the 15th, 30th, 45th and 60th day of exposure and 60th day of recovery. Fish treated with LCT showed behavioural abnormalities compared tothe control, which included reduced swimming activity, loss of equilibrium, vertical hanging and air gulping. The LC_(50) values of LCT were 0.571, 0.380, 0.337 and 0.325 ppm at the exposure time of 24, 48, 72 and 96 h, respectively. Significant reductions (p < 0.05) were observed in the packed cell volume, red blood cell count and haemoglobin concentration values in exposed fish. Initial increase in the value of the white blood cell count was observed, which later declined. Serum glucose increased significantly (p ^ 0.05), while globulin decreased significantly. Albumin did not show any significant difference among tested concentrations. The results revealed that the emulsifiable concentrate form of LCT caused reduction in haematological and biochemical parameters of C. gariepinus. The data obtained in this study provide more information on the potential impacts of LCT on non-target organisms and thus will assist in future ecotoxicological evaluations.