On the suppression of background signals originating from NMR hardware components. Application to zero echo time imaging and relaxation time analysis

摘要

Modern NMR imaging systems used for biomedical research are equipped with B-0 gradient systems with strong maximum gradient strength and short switching time enabling H-1 NMR measurements of samples with very short transverse relaxation times. However, background signal originating from non-optimized RF coils may hamper experiments with ultrashort delays between RF excitation and signal reception. We demonstrate that two simple means, outer volume suppression and the use of shaped B-0 fields produced by higher-order shim coils, allow a considerable suppression of disturbing background signals. Thus, the quality of NMR images acquired at ultrashort or zero echo time is improved and systematic errors in quantitative data evaluation are avoided. Fields of application comprise MRI with ultrashort echo time or relaxation time analysis, for both biomedical research and characterizing porous media filled with liquids or gases. (C) 2015 Elsevier Inc. All rights reserved.