The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells

Wan Xiu-Kun; Yuan Sheng-Ling; Tao Hao-Xia; Diao Li-Peng; Wang Yan-Chun; Cao Cheng; Liu Chun-Jie

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The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells

机译：幽门螺杆菌诱导的TRAF1上调对感染细胞具有抗凋亡作用

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BackgroundTumor necrosis factor receptor-associated factor 1 (TRAF1) is a member of the TRAF family and is dysregulated in diseases, such as atheroma, lymphoma, and solid tumors, but the role of TRAF1 in gastric cancer remains unknown. This study was aimed to investigate the role of TRAF1 in Helicobacter pylori (H. pylori)-related cell apoptosis and gastric carcinogenesis.

机译：背景肿瘤坏死因子受体相关因子1（TRAF1）是TRAF家族的成员，在诸如动脉粥样硬化，淋巴瘤和实体瘤等疾病中表达失调，但是TRAF1在胃癌中的作用仍然未知。这项研究旨在调查TRAF1在幽门螺杆菌（H. pylori）相关的细胞凋亡和胃癌发生中的作用。

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《Helicobacter》 |2016年第6期|共11页
作者
Wan Xiu-Kun; Yuan Sheng-Ling; Tao Hao-Xia; Diao Li-Peng; Wang Yan-Chun; Cao Cheng; Liu Chun-Jie;
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正文语种 eng
中图分类微生物学;
关键词
Helicobacter pylori; TRAF1; NF-B; CagA; apoptosis;

机译：幽门螺杆菌;TRAF1;NF-B;CagA;细胞凋亡;

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专利

1. The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells [J] . Wan Xiu-Kun, Yuan Sheng-Ling, Tao Hao-Xia, Helicobacter . 2016,第6期

机译：幽门螺杆菌诱导的TRAF1上调对感染细胞具有抗凋亡作用
2. Crude Preparations of Helicobacter pylori Outer Membrane Vesicles Induce Upregulation of Heme Oxygenase-1 via Activating Akt-Nrf2 and mTOR–IκB Kinase–NF-κB Pathways in Dendritic Cells [J] . Su Hyuk Ko, Da Jeong Rho, Jong Ik Jeon, Infection and immunity . 2016,第8期

机译：幽门螺杆菌外膜囊泡的粗制品通过激活树突状细胞中的Akt-Nrf2和mTOR–IκB激酶–NF-κB途径诱导血红素加氧酶-1的上调。
3. Crude Preparations of Helicobacter pylori Outer Membrane Vesicles Induce Upregulation of Heme Oxygenase-1 via Activating Akt-Nrf2 and mTOR–IκB Kinase–NF-κB Pathways in Dendritic Cells [J] . Su Hyuk Ko, Da Jeong Rho, Jong Ik Jeon, Infection and immunity . 2016,第8期

机译：幽门螺杆菌外膜囊泡的粗制品通过激活树突状细胞中的Akt-Nrf2和mTOR–IκB激酶–NF-κB途径诱导血红素加氧酶-1的上调。
4. Expression of Suppressors of Cytokine Signaling-3 in Helicobacter pylori-Infected Rat Gastric Mucosal RGM-1 Cells [C] . BORAM CHA, KYUNG HWAN KIM, HIROFUMI MATSUI, Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：细胞因子信号传导抑制剂3在幽门螺杆菌感染的大鼠胃粘膜RGM-1细胞中的表达
5. Secondary analysis of effectivness of tinidazole-containing-quadruple eradication therapy in asymptomatic Helicobacter pylori infected children in El Paso [D] . Prieto-Jimenez, Carmen Aida 2010

机译：EL Pyliancational幽门螺杆菌幽门螺杆菌幽门术中含锡咪唑类含有四肢切除治疗的有效性的二次分析
6. Association between Virulence Factors and TRAF1/4-1BB/Bcl-xL Expression in Gastric Mucosa Infected with Helicobacter pylori [O] . Fen Wang, Xiang Wu, Zhiying Liu, 2015

机译：幽门螺杆菌感染胃黏膜中毒力因子与TRAF1 / 4-1BB / Bcl-xL表达的关系
7. Author correction to Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells [Infect. Immun. 72, 9, (2004) 5019-5026] [O] . Sebkova, L, Pellicanò, A, Monteleone, G, 2014

机译：作者对细胞外信号调节蛋白激酶的校正介导了幽门螺杆菌感染的人胃上皮细胞中白介素17（IL-17）诱导的IL-8分泌[免疫72，9，（2004）5019-5026]

The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells

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