Repair of avulsed ventral nerve roots by direct ventral intraspinal implantation after brachial plexus injury.

摘要

Currently, the authors' research confirms that,in humans, communication between the cord and effector muscles can be re-established after multi-ple nerve root avulsion by the implantation of peripheral nerve grafts. Outcomes are still modest,but the possibility of improvement exists. The technique of reimplantation makes it possible to envisage global repair with the possibility of repair of all avulsed regions. The most important factor that could maximize the extent of functional recovery is reducing the time between the injury and corrective surgery: the diagnosis of avulsion within 10 days and reparative surgery within 3 weeks is the objective. This goal will involve a global re-evaluation of how these patients are managed. The problem of the recovery of sensory function (tactile and fine perception and proprioception) warrants further work.It seems likely that methods combining medullary reimplantation with neurotization will be the best way of correcting these lesions of the brachial plexus. In this context, cross-disciplinary collaboration is probably more important than ever. The place that methods based on reimplantation will have in the final picture remains to be seen. The key question is in which patients should medullary reimplantation be attempted and which method should be used. Moreover, medullary reimplantation should be considered as an adjunct to all other surgical options and should not compromise the chance of the latter modalities to be effective.An important point remains: are physicians going to be able to map out all the boundaries of this question in the future?