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Biofeedback therapy plus anal electrostimulation for fecal incontinence: prognostic factors and effects on anorectal physiology.

机译:生物反馈疗法加肛门电刺激治疗大便失禁:预后因素及其对肛门直肠生理的影响。

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摘要

BACKGROUND: The current literature does not provide unequivocal data on prognostic factors in conservative management of fecal incontinence. Moreover, the physiopathologic effects of pelvic floor rehabilitation on anorectal function are not well understood. Our aim is to identify some prognostic parameters and assess their effects on anorectal physiology of biofeedback therapy plus anal electrostimulation for fecal incontinence. METHODS: We studied prospectively 45 consecutive adult patients with fecal incontinence treated at our institution with biofeedback plus electrostimulation. The outcome parameter was modification of the Wexner Incontinence Score (WIS) at the end of treatment. In addition, we studied the modifications of anorectal manometry and the rectal sensitivity threshold after treatment. RESULTS: At univariate analysis, age, the pretreatment WIS, and the pretreatment resting and maximum squeeze pressures were correlated with the clinical outcome. Patients showed a significant reduction in the rectal sensitivity threshold but no significant change in manometric parameters after treatment. CONCLUSIONS: We identify good sphincter function and mild to moderate symptomatology as favorable prognostic factors in biofeedback and anal electrostimulation therapy. Improvement in rectal sensitivity can be implicated in symptomatic improvement. The impossibility of correlating the clinical results with the effects on anorectal physiology suggests a nonspecific effect of conservative treatment.
机译:背景:目前的文献并没有提供关于大便失禁保守治疗中预后因素的明确数据。此外,骨盆底康复对肛门直肠功能的生理病理学影响还不清楚。我们的目的是确定一些预后参数,并评估其对生物反馈疗法加肛门电刺激治疗大便失禁对肛门直肠生理的影响。方法:我们对在我院接受生物反馈加电刺激治疗的连续45例成人大便失禁患者进行了前瞻性研究。结果参数是治疗结束时韦克斯纳氏失禁评分(WIS)的修改。此外,我们研究了肛门直肠测压的修改和治疗后的直肠敏感性阈值。结果:单因素分析显示,年龄,治疗前WIS,治疗前静息和最大挤压压力与临床结局相关。治疗后患者的直肠敏感性阈值明显降低,但测压参数无明显变化。结论:我们认为良好的括约肌功能和轻度至中度症状是生物反馈和肛门电刺激治疗的有利预后因素。直肠敏感性的改善可能与症状改善有关。不可能将临床结果与对肛肠生理的影响相关联,这表明了保守治疗的非特异性作用。

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