首页> 外文期刊>World journal for pediatric & congenital heart surgery >Aortic Cusp Extension for Surgical Correction of Rheumatic Aortic Valve Insufficiency in Children
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Aortic Cusp Extension for Surgical Correction of Rheumatic Aortic Valve Insufficiency in Children

机译:小儿主动脉瓣延长术治疗风湿性主动脉瓣关闭不全

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Surgical management of aortic insufficiency in the young is problematic because of the lack of an ideal valve substitute. Potential advantages of aortic valve repair include low incidences of thromboembolism and endocarditis, avoiding conduit replacements, the maintenance of growth potential, and improved quality of life. Aortic valve repair is still far from fulfilling the three key factors that have allowed the phenomenal development of mitral valve repair (standardization, reproducibility, and stable long-term results); however, techniques of aortic valve repair have been refined, and subsets of patients amenable to repair have been identified. We have focused on the oldest technique of aortic valve repair, cusp extension, focusing on children with rheumatic aortic insufficiency. Among 77 children operated from 2003 to 2007, there was one early death from ventricular failure and one late death from sudden cardiac arrhythmia. During a mean follow-up of 12.8 + 5.9 years, there were 16 (20.5%) reoperations on the aortic valve, at a median of 3.4 years (range, 2 months to 18.3 years) from repair. Freedom from aortic valve reoperation was 96.2% ± 2.2% at I year, 94.9% ± 2.5% at 2 years, 88.5% + 3.6% at 5 years, 81.7% ± 4.4% at 10 years, 79.7% ± 4.8% at 15 years, and 76.2% + 5.7% at 20 years. Although aortic cusp extension is technically more demanding, it remains particularly more suitable in the context of evolving rheumatic aortic insufficiency in children with a small aortic annulus as a bridge surgical approach to late aortic valve replacement with a larger valvular prosthesis.
机译:由于缺乏理想的瓣膜替代物,年轻人的主动脉瓣关闭不全的外科治疗存在问题。主动脉瓣修复的潜在优势包括血栓栓塞和心内膜炎的发生率低,避免更换导管,维持生长潜力以及改善生活质量。主动脉瓣修复仍远未达到三尖瓣修复显着发展的三个关键因素(标准化,可重复性和长期稳定结果);然而,主动脉瓣修复技术已得到完善,并且已经确定了适合修复的患者亚组。我们专注于最古老的主动脉瓣修复技术,即尖瓣扩张,关注风湿性主动脉瓣关闭不全的儿童。在2003年至2007年手术的77名儿童中,有1名因心室衰竭而早亡,另1名因突发心律不齐而死亡。在平均12.8 + 5.9年的随访期间,主动脉瓣再手术16次(20.5%),平均修复时间为3.4年(范围2个月至18.3年)。第1年主动脉瓣再造的自由度为96.2%±2.2%,第2年为94.9%±2.5%,第5年为88.5%+ 3.6%,第10年为81.7%±4.4%,第15年为79.7%±4.8% ,以及20年后的76.2%+ 5.7%。尽管在技术上对主动脉瓣的延伸要求更高,但在小动脉主动脉瓣环变的儿童风湿性主动脉瓣关闭不全的情况下,它仍然是特别合适的方法,可作为桥梁外科手术方法,用较大的瓣膜假体替代晚期主动脉瓣。

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