Two single-centre, non-blinded, randomized, controlled trials recently reported the effect of bariatric surgery on the rate of diabetes control. Bariatric surgery was shown to be far more effective than conventional or intensive medical therapy in inducing remission and controlling hyperglycaemia (with fewer medicines or none). The present studies were the first two randomized controlled trials comparing medical therapy with surgical measures for weight loss besides gastric banding. They add to the accumulating evidence that bariatric surgery improves glycaemic control in people with diabetes.u Other benefits of surgery included improvement in weight, waist circumference, lipids, blood pressure and markers of inflammation. In a large, non-randomized matching control trial, Sjostrom et al. have shown that bariatric surgery for severe obesity is associated with long-term weight loss, remission of diabetes and decreased cardiovascular and overall mortality (Table I).
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