Equine sarcoids - Part 1: Clinical presentation and epidemiology.

摘要

Equine sarcoids are the most common skin tumors in horses and other equids. In their pathogenesis, the bovine papillomavirus (BPV) plays a major role. Many clinical manifestations have been described, ranging from small single lesions to multiple aggressively growing masses. Histopathologically, it is considered as a biphasic tumor with epidermal hyperplasia and subepidermal proliferation of transformed fibroblasts. The diagnosis can be made clinically, histopathologically and/or by detection of BPV DNA. Sarcoids can appear on any part of the body, but they are mostly localized on the ventral abdomen, the paragenital region, head and limbs. Sarcoids occur independent of breed, coat color, sex or age, but they develop more commonly in young adults and certain families and breeds are more vulnerable than others. Transmission of BPV is supposed to happen from cattle to horse or from horse to horse, possibly via insects.