Have a cat presenting with hypertension? Hypokalemia? Here's why you should add this disorder to your differential diagnosis list. Primary hyperaldosteronism, also referred to as Conn's syndrome or aldosteronism, is an adrenal disorder characterizedby excessive and independent secretion of aldosterone. Conn first described primary hyperaldosteronism in people in 1955 and discussed three hallmarks—hypertension, hypokalemia, and increased serum aldosterone concentrations. Primary hyperaldosteronismwas originally thought to be a rare condition, but the prevalence in people was found to be 6% in all patients with arterial hypertension and about 11% in patients with therapy-resistant hypertension.
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