首页> 外文期刊>Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research >Valuation of EQ-5D health states in Poland: first TTO-based social value set in Central and Eastern Europe.
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Valuation of EQ-5D health states in Poland: first TTO-based social value set in Central and Eastern Europe.

机译:波兰EQ-5D健康状态的评估:中欧和东欧首次设定的基于TTO的社会价值。

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OBJECTIVE: Currently, there is no EQ-5D value set for Poland. The primary objective of this study was to elicit EQ-5D Polish values using the time trade-off (TTO) method. METHODS: Face-to-face interviews with visitors of inpatients in eight medical centers in Warsaw, Skierniewice, and Pulawy were carried out by trained interviewers. Quota sampling was used to achieve a representative sample of the Polish population with regard to age and sex. Modified protocol from the Measurement and Value of Health study was used. Each respondent ranked 10 health states and valued 4 health states using the visual analog scale and 23 using the TTO. Mean and variance stability tests were performed to determine whether using a larger number of health states per respondent would yield credible results. Modeling included random effects and random parameters models. RESULTS: Between February and May 2008, 321 interviews were performed. Modeling based on 6777 valuations resulted in an additive model with all coefficients statistically significant, R(2) equal to 0.45, and value -0.523 for the worst possible health state. Means and variance did not differ significantly for states valued in the middle and at the end of the TTO exercise. CONCLUSIONS: This is the first EQ-5D value set based on TTO in Central and Eastern Europe so far. Because the values differ considerably from those elicited in Western European countries, its use should be recommended for studies in Poland. Increasing the number of health states that each respondent is asked to value using TTO seems feasible and justifiable.
机译:目的:目前,波兰尚未设置EQ-5D值。这项研究的主要目的是使用时间权衡(TTO)方法得出EQ-5D波兰值。方法:由受过训练的访调员对华沙,斯基尼涅维采和普拉维八个医疗中心的住院患者进行面对面的访谈。配额抽样用于获得波兰人口在年龄和性别方面的代表性样本。使用来自“测量与健康价值”研究的改进方案。每位受访者使用视觉模拟量表对10种健康状态进行排名,并使用TTO对23种健康状态进行评估,将其评估为23种。进行了均值和方差稳定性测试,以确定每个受访者使用大量健康状况是否会产生可信的结果。建模包括随机效应和随机参数模型。结果:在2008年2月至5月之间,进行了3​​21次访谈。基于6777评估的建模得出了一个加法模型,所有系数在统计上均显着,R(2)等于0.45,对于最差的健康状况,其值为-0.523。在TTO演习的中间和结尾,各州的均值和方差没有显着差异。结论:这是迄今为止在中欧和东欧基于TTO的第一个EQ-5D值集。由于这些值与西欧国家得出的值有很大差异,因此建议在波兰进行研究时建议使用该值。要求每个响应者使用TTO评估其健康状况的数量似乎是可行和合理的。

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