Kidney-Pancreas Transplantation Does Not Improve Retinal Arterial Flow Velocities in Type 1 Diabetic Uremic Patients

摘要

After our recent article published in Transplantation (i), we investigated the retinal arterial flow variation 1 year after transplant in kidney-pancreas (KP) and kidney-alone (KA) type 1 diabetic uremic transplanted patients. In our previous report, a statistically significant increase of retinal blood flow velocities was found 1 year after islet transplant alone (ITA) in 10 type 1 diabetic patients (mean age=38.0+-2.2 years; diabetes duration before transplant=24.9 +-2.3 years), unaffected or affected by mild or moderate nonproliferative retinopathy.We embarked in a prospective study evaluating the central retinal artery (CRA) of 10 KP (mean age=41.1+-5.9 years; diabetes duration before trans-plant=26.0+-3.8 years) and 10 KA (mean age=41.6+-5.3 years; diabetes duration before transplant=30.8+-4.7 years) transplanted patients.