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Learning to see: patterned visual activity and the development of visual function.

机译:学着看:有图案的视觉活动和视觉功能的发展。

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摘要

To successfully interact with their environments, developing organisms need to correctly process sensory information and generate motor outputs appropriate to their size and structure. Patterned sensory experience has long been known to induce various forms of developmental plasticity that ultimately shape mature neural circuits. These same types of plasticity also allow developing organisms to respond appropriately to the external world by dynamically adapting neural circuit function to ongoing changes in brain circuitry and sensory input. Recent work on the visual systems of frogs and fish has provided an unprecedented view into how visual experience dynamically affects circuit function at many levels, ranging from gene expression to network function, ultimately leading to system-wide functional adaptations.
机译:为了与环境成功互动,发展中的生物需要正确处理感官信息并生成适合其大小和结构的运动输出。长期以来,已知图案化的感觉体验会诱发各种形式的发育可塑性,最终形成成熟的神经回路。这些相同类型的可塑性还允许发育中的生物体通过动态地使神经回路功能适应大脑回路和感觉输入的持续变化来对外界做出适当的反应。关于青蛙和鱼的视觉系统的最新工作为视觉体验如何动态地影响从基因表达到网络功能的许多层次的电路功能提供了空前的见解,最终导致了系统范围的功能适应。

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