Pre-transplant donor-specific Interferon-gamma-producing cells and acute rejection of the kidney allograft

摘要

Background: Our retrospective study included a cohort of 47 patients who underwent living donor kidney transplantation. The pre-transplant frequencies of donor-specific Interferon-gamma (IFN-gamma) producing cells were defined using enzyme-linked immunosorbent spot (ELISpot) assay and correlated with incidence of acute cellular (ACR), antibody-mediated rejection (AMR) and kidney graft survival up to one year after transplantation.