Proceedings of the 15th Workshop on Trace Elements and Electrolytes in Oncology Akte 1/2014 (Selected Abstracts) Kassel, Germany, May 2-4, 2014

摘要

A magnesium deficiency can result in a disturbed vitamin D metabolism and decreased vitamin D concentrations in humans. Both results in increased interleukin levels and developing arteriosclerosis. Especially elderly, hypertensive patients and diabetics are risk groups for arteriosclerosis resulting in stroke or heart failure with a significant increase in morbidity and mortality. We investigated magnesium, vitamin D, and interleukines in different clinical subgroups finding interesting results. Especially in the elderly, hypertensive diabetics magnesium and vitamin D concentrations were found significantly decreased as compared to controls (p < 0.05). In all of those patients interleukine levels were significantly increased (p < 0.05). Most of these patients additionally showed an increased media thickness. In conclusion, a magnesium and vitamin D deficiency in hypertension and diabetes mellitus has to be supplemented in a sufficient amount of up to 300 - 500 mg magnesium and at least 1,000 - 2,000 I.E. vitamin D daily.