ANTIOXIDANT ACTIVITY OF THIAMINE AND ITS STRUCTURAL ANALOGS IN REACTIONS WITH ELECTROCHEMICALLY GENERATED HYDROXYL RADICALS AND HYDROGEN PEROXIDE

摘要

We have used differential pulse voltammetry on platinum and copper cathodes to study the antioxidant activity of thiamine (vitamin B1) and its structural analogs. The results indicate that the activity of thiamine relative to the hydroxyl radical is lower than the activity of 3-benzyl-4-methyl-5-(2-hydroxyethyl)thiazolium chloride. At the same time, thiamine can more efficiently react with hydrogen peroxide and bind divalent iron ions.