Have we reached a turning point in the diagnosis and treatment of canine lymphoma?

摘要

Lymphoma is the most common haematopoietic neoplasm in dogs (Dobson et al., 2002), and its significance is illustrated by a quick web-search that identifies >1000 related references. Fortunately the neoplasm responds well to treatment and in approximately 80% of the cases complete remission can be achieved. Nevertheless, a cohort remains that is refractory to therapy and the animals have a short survival time (MacEwen et al., 1987 E.G. MacEwen, A.A. Hayes, R.E. Matus and I.D. Kurzman, Evaluation of some prognostic factors for advanced multicentric lymphosarcoma in the dog: 147 cases (1978–1981). Journal of the American Veterinary Medical Association, 190 (1987), pp. 564–567. MacEwen et al., 1987).