A transposition is an operation that exchanges two adjacent substrings. Transpositions over permutations, the sequences with no repeated symbols, are related to genome rearrangements. If one of the substrings is restricted to a prefix then it is called a prefix transposition. The prefix transposition distance between a pair of strings (permutations) is the minimum number of prefix transpositions required to transform a given string (permutation) into another given string (permutation). For a permutation of length n, we improve the current prefix transposition distance upper bound of n - log_8 n to n - log_(9/2) n. For arbitrary strings, we prove new prefix transposition distance upper and lower bounds. For binary strings of length n, we show that n/2 is an upper bound. We show that the prefix transposition distance problem is NP-complete for binary strings.
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