Bupropion plus nicotine replacement no better than replacement alone

摘要

Clinical question Does the addition of bupropion to nicotine replacement and counselling improve smoking cessation rates?Bottom line Addition of bupropion (Zyban) does not further increase long-term smoking cessation rates in those who receive nicotine replacement and cognitive-behavioural counselling.Quit rates at one year were similar in both groups - 22 per cent and 28 per cent (P non-significant).