Blast effector proteins may pave the way for hyphal invasion.Comments Comment on: Plant Cell. 2010 Apr;22(4):1388-403; PMID: 20435900

摘要

The rice blast fungus (Magnaporthe oryzae) is an economically important pathogen that infects rice, wheat, and other cereal crops. The fungus enters leaves via dome-shaped appressoria that develop from germinated spores and forms invasive hyphae (IH) that undergo pseudohyphal growth inside the invaded plant cells. Once IH have completely filled a cell, they constrict and enter neighboring cells, possibly via plasmodesmata. IH are separated from the plant's cytoplasm by a plant-derived membrane, the extrainvasive hyphal membrane (EIHM) (Kankanala et al., 2007). IH express many novel biotrophy-associated secreted (BAS) proteins, including effector proteins, which promote disease by altering the plant's metabolism and blocking defense responses (Mosquera et al., 2009). Successful fungal colonization relies on the transport of effector proteins across the EIHM, from the IH to the cytoplasm of the host.