Cardiovascular function in humans during exercise: role of the muscle pump.

摘要

Both central and local factors play an important role in the regulation of skeletal muscle blood flow during exercise. The skeletal muscle pump is thought to be crucial in coordinating the local and systemic blood flow responses during exercise (Rowell, 1993). During the concentric phase of muscle contraction there is expulsion and central mobilization of peripheral venous blood, thus facilitating venous return and increasing stroke volume (SV) and cardiac output (Q). Indeed, a single muscle contraction has been shown to be effective at emptying the venous vessels and enhancing the central trans-location of more than 40% of the intramuscular blood volume (Stewart et al. 2004). By improving Q potential to match that of active muscle vasodilatation, muscle pump-induced displacement of blood centrally can, indirectly promote higher exercise hyperaemia.