Exercise training, inflammation and heart failure: working out to cool down.

摘要

Heart failure (HF) is a common end-stage phenotype of a variety of conditions that impair myocardial performance and/ or cause long-term cardiac overload. The HF syndrome involves progressive functional impairment due to ongoing remodelling that may outlast the initiating cause. Awareness of the importance of adverse remodelling has led to extensive investigation of the underlying mechanisms and potential preventive interventions.