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Delayed optic nerve decompression for indirect optic nerve injury.

机译:延迟性视神经减压可导致间接视神经损伤。

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摘要

OBJECTIVE: To test the efficacy of delayed optic nerve decompression in traumatic optic nerve injury. STUDY DESIGN: Critical analysis of Proforma-based, prospectively accrued data of all cases with injury to surgery interval of greater than 2 weeks. METHODS: Thirty-five cases with a median injury to surgery interval of 56 days (range, 16-374 d). Surgical decompression was undertaken only in cases that continued to have poor vision after treatment with steroids in conventional doses (1 mg/kg prednisolone). Pre- and postoperative visual acuity measurements were converted to the logMAR scale of visual acuity and the percentage of visual improvement was calculated. RESULTS: Surgery was universally unrewarding in all 9 cases with persistent and complete blindness of greater than 2 weeks and no response to steroid therapy. Of the cases with some residual vision, 20 of 26 cases improved (mean percentage improvement, 41.0 +/- 5.7%). Cases were categorized on the basis of the injury to surgery interval into groups of 2 weeks to 2 months, 2 months to 4 months, and greater than 4 months. No significant difference was demonstrated in the probability or quantum of improvement in these groups (P =.97). CONCLUSIONS: Optic nerve decompression remains useful as a salvage procedure for conventional dose steroid failed cases of traumatic optic neuropathy. In cases that are not completely blind, vision can be improved even when surgery is undertaken a few months after the injury.
机译:目的:探讨延迟性视神经减压术在外伤性视神经损伤中的疗效。研究设计:对所有间隔时间超过2周的病例进行基于形式的前瞻性应计数据的严格分析。方法:35例中位手术间隔为56天(范围16-374 d)。仅在以常规剂量(1 mg / kg泼尼松龙)进行类固醇治疗后视力仍较差的情况下才进行手术减压。术前和术后视力测量值转换为logMAR视力表,计算出视力改善的百分比。结果:所有9例持续且完全失明超过2周且对类固醇治疗无反应的患者普遍无手术治疗。在残留视力的病例中,有26例中有20例得到了改善(平均百分率提高了41.0 +/- 5.7%)。根据对手术间隔的伤害,将病例分为2周至2个月,2个月至4个月以及大于4个月。在这些组中,改善的可能性或数量没有显着差异(P = 0.97)。结论:对于常规剂量的类固醇失败的创伤性视神经病变患者,视神经减压术仍可作为挽救方法。在并非完全失明的情况下,即使受伤后几个月进行手术,也可以改善视力。

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