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Identification of MERS-CoV in dromedary camels

机译:单峰骆驼中MERS-CoV的鉴定

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One health-an initiative designed to integrate human and veterinary health-received a boost in The Lancet Infectious Diseases. A multidisciplinary team of scientists from the Netherlands, Qatar, and the UK report the first definitive isolation of the Middle East respiratory syndrome coronavirus (MERS-CoV) in a non-human animal species, dromedary camels.1 Phylogenetic analysis of the 4.2 kb partial viral sequence obtained from one animal show the virus to be almost identical to isolates obtained from two human cases who had had contact with the camels on the affected farm. The affected smallholding is part of a much larger farm complex located about 30 km northwest of Doha, Qatar, which has been the subject of intensive epidemiological investigation since the diagnosis of the first human case on the farm 2 months ago.2 Although the virus has only been sequenced from one camel to date, some virological evidence of infection was reported in 11 of 14 camels on the farm, and serological evidence of exposure to a MERS-CoV-like virus was noted in all of them.
机译:一项旨在整合人类和兽医健康的健康倡议获得了“柳叶刀传染病”的推动。来自荷兰,卡塔尔和英国的多学科科学家团队报告了在非人类动物单峰骆驼中首次确定性分离出中东呼吸综合征冠状病毒(MERS-CoV)。1对4.2 kb部分序列的系统发育分析从一只动物获得的病毒序列显示该病毒与从两名与该农场的骆驼接触过的人类病例获得的分离株几乎相同。受到影响的小农户是位于卡塔尔多哈西北约30公里处的一个大型农场综合体的一部分,自2个月前在该农场诊断出第一例人类病例以来,就一直对其进行深入的流行病学调查。2迄今为止仅从一头骆驼进行了测序,在农场的14头骆驼中有11例报道了一些病毒学感染证据,并且在所有这些中都发现了暴露于MERS-CoV样病毒的血清学证据。

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