Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient.

摘要

Venous thromboembolism (VTE) in seriously injured patients is a common problem that can potentially lead to substantial morbidity, mortality, and resource expenditure. In fact, patients recovering from trauma have the highest rate of VTE among all subgroups of hospitalized patients. Depending on the patient cohort and diagnostic modality, rates of deep venous thrombosis (DVT) and pulmonary embolism (PE) may be as high as 40% and 20%, respectively. Not only is the development of VTE in the form of a massive PE a cause of late death in the injured patient, VTE development anytime after injury complicates management and can lead to significant long-term sequelae. To reduce the risk of VTE, many practitioners administer mechanical or pharmacologic thromboprophylaxis or both.