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首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >The role of silicone stents in the treatment of cicatricial tracheal stenoses.
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The role of silicone stents in the treatment of cicatricial tracheal stenoses.

机译:硅胶支架在治疗瘢痕性气管狭窄中的作用。

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OBJECTIVE: Tracheal stenting for cicatricial stenoses is reserved for patients whose lesions are deemed inoperable for local or general reasons. The aim of our study was to verify the long-term results of silicone tracheal stents in such a clinical setting. METHODS: Clinical data of 45 patients treated by tracheal silicone stents, between 1987 and 1999, were reviewed. All patients had highly symptomatic cicatricial stenoses; they were selected for stenting rather than for surgery because of local and general conditions. This series has been divided in two groups according to the purpose of stenting: bridge to surgery or definitive treatment. Follow-up ranged between 12 and 83 months. Twenty-seven patients received a Montgomery T tube (Hood Laboratories, Pembroke, Mass), 16 a Dumon stent (Novatech, Plan de Gras, France), and 2 a Dynamic stent (Rusch, Kernen, Germany). RESULTS: No procedure-related mortality was observed. Nine patients underwent curative resection and reconstruction after a variable stenting period; one had a recurrent stenosis and was treated for palliation with a T tube. Tracheal stenting was performed for palliation as a definitive treatment in 37 patients. Among this group, 11 patients died of unrelated causes at a median of 10 months after the endoscopic treatment. The stent was permanently removed in 10 after a median interval of 32 months (range 9-70 months); in 4 others, symptomatic recurrence of the stenosis was observed within 6 weeks of stent removal. None of the patients successfully decannulated had a completely normal tracheal lumen but all remained asymptomatic because the residual stenosis was mild or well tolerated for concomitant limitation of physical activity. CONCLUSIONS: Long-term treatment with a silicone stent was safe and well tolerated in cicatricial tracheal stenoses. This procedure can be considered as a bridge to curative surgery or as a definitive treatment. The latter, generally performed for palliation, may provide satisfactory therapeutic results in selected patients, even in the presence of severe circumferential stenoses.
机译:目的:为因局部或一般原因而认为病变无法手术的患者保留气管支架用于瘢痕狭窄。我们的研究目的是验证在这种临床环境中硅胶气管支架的长期效果。方法:回顾性分析了1987年至1999年间经气管硅胶支架治疗的45例患者的临床资料。所有患者均具有高度症状性瘢痕性狭窄;由于局部和一般情况,他们被选择植入支架而不是手术。根据支架的目的,该系列分为两组:通向手术或确定性治疗。随访时间为12到83个月。二十七例患者接受了蒙哥马利T型管(Hood Laboratories,彭布罗克,马萨诸塞州),16例Dumon支架(Novatech,法国普朗德格拉斯)和2例动态支架(Rusch,德国克嫩,德国)。结果:未观察到与手术相关的死亡率。 9例患者在不同的支架置入期后进行了根治性切除和重建;一个患有复发性狭窄,并用T管进行姑息治疗。气管支架置入术可作为缓解患者37例的最终治疗方法。在该组中,有11例患者在内镜治疗后中位10个月内死于无关原因。在中位间隔32个月(9-70个月)后的10个月内,将支架永久性取出。在另外4个中,在移除支架的6周内观察到狭窄的症状复发。没有成功进行脱皮的患者中没有一个患者的气管腔完全正常,但都没有症状,因为残余狭窄程度较轻或对身体活动的限制耐受性良好。结论:硅胶支架长期治疗在瘢痕性气管狭窄中安全且耐受性良好。该程序可被视为治愈性手术或确定性治疗的桥梁。后者通常用于缓解症状,即使在存在严重的周围狭窄的情况下,也可以在选定的患者中提供令人满意的治疗效果。

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