首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Palliative pulmonary artery banding versus anatomic correction for congenitally corrected transposition of the great arteries with regressed morphologic left ventricle: Long-term results from a single center
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Palliative pulmonary artery banding versus anatomic correction for congenitally corrected transposition of the great arteries with regressed morphologic left ventricle: Long-term results from a single center

机译:姑息性肺动脉绑扎与解剖矫正相结合,先天校正左大动脉形态退化的大动脉移位:单个中心的长期结果

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Objective: We aimed to compare the long-term results between palliative pulmonary artery banding and anatomic correction for congenitally corrected transposition of the great arteries with regressed morphologic left ventricle.Methods: From 2003 to 2012, 40 consecutive patients underwent first-stage pulmonary artery banding. The second-stage operation-double switch-was performed in 15 patients (double-switch group). The other 25 patients retained pulmonary artery banding without further operation (pulmonary artery banding group). Inhospital mortality, long-term mortality, and heart function were studied as primary outcomes.Results: The median time of follow-up was 3.4 ± 0.7 years (range, 6 months-9.5 years). Overall survival rate was 66.7%in the double-switch group versus 96.0%in the pulmonary artery banding group (P = .03). The ratio of New York Heart Association functional class I-II (80.0% vs 95.9%; P = .02) and the mean functional left ventricle ejection fraction (51.4% ± 9.6% vs 61.0% ± 6.4%; P = .01) were higher in the pulmonary artery banding group at follow-up. In univariate analysis, age at pulmonary artery banding was the only risk factor for late deaths (odds ratio, 7.30; P = .01) and left ventricle dysfunction (odds ratio, 4.77; P = .03) after the double switch. For patients who experienced prolonged pulmonary artery banding, mean oxygen saturation was 95% ± 3.1% and the trans-banding pressure gradient was 46.9 ± 21.5 mm Hg.Conclusions: In patients with congenitally corrected transposition of the great arteries with deconditioned morphologic left ventricle pulmonary artery banding may be considered an ideal procedure because it allows left ventricle training while improving tricuspid regurgitation. Compared with the double-switch procedure after pulmonary artery banding, prolonged palliative pulmonary artery banding provided a lower mortality rate and indicated better cardiac function.
机译:目的:我们比较比较姑息性肺动脉束缚带和解剖矫正术对先天性校正左动脉形态退化的大动脉移位的效果。方法:2003年至2012年,连续40例患者接受了第一阶段肺动脉束缚。 15例患者(双开关组)进行了第二阶段双开关手术。另外25例患者保留了肺动脉束带,无需进一步手术(肺动脉束带组)。以院内死亡率,长期死亡率和心功能为主要结果。结果:随访的中位时间为3.4±0.7年(范围为6个月至9.5年)。双转换组的总生存率为66.7%,而肺动脉束缚组的总生存率为96.0%(P = .03)。纽约心脏协会功能性I-II级的比率(80.0%vs 95.9%; P = .02)和平均功能性左心室射血分数(51.4%±9.6%vs 61.0%±6.4%; P = 0.01)随访时肺动脉束带组的血脂水平较高。在单因素分析中,在两次切换后,肺动脉束带的年龄是导致晚期死亡(比值比为7.30; P = 0.01)和左心室功能障碍(比值比为4.77; P = .03)的唯一危险因素。对于经历长时间肺动脉束带的患者,平均氧饱和度为95%±3.1%,跨束带压力梯度为46.9±21.5 mm Hg。结论:先天性纠正左大动脉形态受损的大动脉移位的患者动脉束带术可以被认为是理想的手术方法,因为它可以在改善三尖瓣关闭不全的同时进行左心室训练。与肺动脉束缚后双刀切手术相比,延长姑息性肺动脉束缚可降低死亡率,并显示更好的心功能。

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