Mercury(II)-mediated cleavage of cyclopropylcarbinols by an intramolecular sulfinyl group as a stereo-and regioselective route to stereotriads and stereotetrads

摘要

Mercury(II) salt mediated opening of cyclopropylcarbinols by an intramolecular sulfinyl group is disclosed. All four diastereomeric stereotriads have been prepared from cis-and trans-disubstituted cyclopropanes. The trisubstituted cyclopropanes also react regio-and stereoselectively to afford products possessing quaternary stereogenic centers. The reaction is clean and general.