CHEMICAL CONSTITUENTS AND CYTOTOXIC ACTIVITY OF Smallanthus maculatus

摘要

Smallanthus maculatus (Cav) H.Rob.(Asteraceae,nomenclatural synonym: Polymnia maculata Cav.Icon.[1,2]) is used by the Highlands Mayas of Chiapas,Mexico,for the treatment of gastrointestinal diseases [3].To our knowledge,no phytochemical investigation has been reported on S.maculatus;however,from P.maculata has been isolated ent-kaur-16-en-19-oic acid,kauradiene-9,16-dioic acid,polymatin A,polymatin B,polymatin C [4],maculatin [5],melampodin D,and 9-desacetoxymelcanthin F [6];consequently,these are chemical constituents of S.maculatus in reality.