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Management of acute type B aortic dissections and acute limb ischemia.

机译:急性B型主动脉夹层和急性肢体缺血的处理。

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摘要

AIM: The aim of this study was to review the management of acute type B aortic dissection (TBAD) with acute limb ischemia. A search using the "Pubmed" resulted in 254 records by combining the Medical Subject Heading keywords (listed separately). The articles were assessed for their validity, correct pathology and patient cohort. Inclusion criteria included all patients with complicated acute TBAD who were candidates for open of thoracic endovascular aortic repair (TEVAR). The exclusion criteria included type A, asymptomatic acute or chronic TBAD, penetrating ulcer or intramural hematoma. TBAD with limb ischemia has a poor prognosis if not diagnosed, triaged and treated promptly. Clinical presentation and diagnostic strategy as well as various imaging are reviewed. Early mortality rate for complicated acute TBAD (with malperfusion to lower extremity) is 12%. The management has moved from open operation to primary TEVAR. In cases with anatomic obstruction, open surgical techniques such as femoral-femoral bypass, axillo-femoral bypass or surgical fenestration can be successful in relief of malperfusion to the affected limb. One-year-survival rates are 85%. A complete to partial reverse aortic remodeling occurred in 78% of survivors of acute TBAD, if primary TEVAR is applied. Acute TBAD with limb ischemia remains a clinical challenge that requires prompt diagnosis and treatment. TEVAR of acute TBAD is associated with relatively low morbidity and mortality, and is more often used as primary approach for patients with limb ischemia. The outcomes with TEVAR compare favorably to the open repair, and initiate reverse aortic remodeling in majority of the survivors.
机译:目的:本研究的目的是回顾急性肢体缺血的急性B型主动脉夹层(TBAD)的管理。通过结合“医学主题词”关键字(单独列出),使用“已公开”进行的搜索产生了254条记录。对文章的有效性,正确的病理学和患者队列进行了评估。纳入标准包括所有患有复杂急性TBAD的患者,这些患者均应行胸腔内血管主动脉修复术(TEVAR)。排除标准包括A型,无症状的急性或慢性TBAD,穿透性溃疡或壁内血肿。如果不及时诊断,分类和治疗,伴有肢体缺血的TBAD预后不良。审查了临床表现和诊断策略以及各种影像学。复杂的急性TBAD(灌注不良至下肢)的早期死亡率为12%。管理层已从开放运营转移到主要TEVAR。在解剖学障碍的情况下,开放式手术技术(如股-股旁路,腋股-股旁路或开窗术)可以成功缓解对患肢的灌注不足。一年生存率是85%。如果应用原发性TEVAR,则在78%的急性TBAD幸存者中会发生完全或部分的主动脉反向重构。患有肢体缺血的急性TBAD仍然是一项临床挑战,需要迅速诊断和治疗。急性TBAD的TEVAR与较低的发病率和死亡率相关,并且更经常用作肢体缺血患者的主要治疗方法。 TEVAR的结果优于开放性修复,并在大多数幸存者中引发了主动脉逆向重构。

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