Case anecdotes, comments and opinions

摘要

Hemolysis is a known complication of durable continuous-flow left ventricular assisfc devices (CF-LVADs),1 and is thought to result from shear force exerted on circulating red blood cells (RBCs). This mechanical injury may be influenced by a number of factors, including device positioning and pump thrombosis, although the pathophysiology of LVAD-related hemolysis remains poorly understood. We reviewed the CF-LVAD experience at our institution and report on a novel association between glucose-6-phosphate dehydrogen-ase (G6PD) deficiency and clinically significant hemolysis.