SYNTHESIS OF 2-(N-BENZOYLIMINO)-N-(9,10-DIOXO- 9,10-DIHYDROANTHRACEN-1-YL)THIAZOLES

摘要

N-Aroylthioureas hold a significant promise for the synthesis of such heterocycles as imidazolidine-2-thiones [1, 2], 2-aroyliminothiazolines [3-5], 1,2,4-triazoles [6], 1,3-thiazines [7], and indeno[1,2-d]-[1,3]thiazepines [8]. Of particular interest are 2-iminothiazolines, which are characterized by a wide range of biological properties [9-11]. For example, the thiazol-2-imine fragment is a structural fragment in muscarinic agonists, as well as antifungal, hypolipidemic, antidiabetic, anti-inflammatory, analgesic, and anti-shistosomiasis compounds [5]. Thiazoline derivatives are also used as insecticides and plant growth regulators [5].