Phosphorylation of Furfural by Secondary Phosphine Oxides

摘要

Nucleophilic addition of secondary phosphine oxides to furfural takes place under mild conditions and gives quantitative yields of 2-(diorganylphosphorylhydroxymethyl)furans, which are polyfunctional building blocks for organic synthesis and prospective amphiphilic ligands for the design of metal complex catalysts.