'Auto-anti-IgE': Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation

Chan Yih-Chih; Ramadani Faruk; Santos Alexandra F.; Pillai Prathap; Ohm-Laursen Line; Harper Clare E.; Fang Cailong; Wu Shih-Ying; Ying Sun; Corrigan Christopher J.; Gould Hannah J.

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'Auto-anti-IgE': Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation

机译：“自身抗IgE”：天然存在的IgG抗IgE抗体可能会抑制变应原诱导的嗜碱性粒细胞活化

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Background: Naturally occurring IgE-specific IgG autoantibodies have been identified in patients with asthma and other diseases, but their spectrum of functions is poorly understood.

机译：背景：已在哮喘和其他疾病患者中鉴定出天然存在的IgE特异性IgG自身抗体，但对其功能范围了解甚少。

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来源
《The Journal of Allergy and Clinical Immunology》 |2014年第6期|共8页
作者
Chan Yih-Chih; Ramadani Faruk; Santos Alexandra F.; Pillai Prathap; Ohm-Laursen Line; Harper Clare E.; Fang Cailong; Wu Shih-Ying; Ying Sun; Corrigan Christopher J.; Gould Hannah J.;
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正文语种 eng
中图分类医学免疫学;
关键词
Asthma; autoantibodies; IgE; basophil activation; basophil inhibition;

机译：哮喘;自身抗体;IgE;嗜碱性粒细胞活化;嗜碱性粒细胞抑制;

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专利

1. "Auto-anti-IgE": Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation [J] . Chan Yih-Chih, Ramadani Faruk, Santos Alexandra F., The Journal of Allergy and Clinical Immunology . 2014,第6期

机译：“自身抗IgE”：天然存在的IgG抗IgE抗体可能会抑制变应原诱导的嗜碱性粒细胞活化
2. Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation. [J] . Vrtala S, Ball T, Spitzauer S, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1998,第12期

机译：用纯化的天然和重组变应原免疫可诱导小鼠IgG1抗体，该抗体识别与人IgE类似的表位，并抑制人IgE-变应原相互作用和变应原诱导的嗜碱性粒细胞脱粒。
3. Immunization with Purified Natural and Recombinant Allergens Induces Mouse IgG1 Antibodies That Recognize Similar Epitopes as Human IgE and Inhibit the Human IgE-Allergen Interaction and Allergen-Induced Basophil Degranulation [J] . Susanne Vrtala, Tanja Ball, Susanne Spitzauer, The journal of immunology . 1998,第12期

机译：纯化的天然和重组过敏原的免疫诱导小鼠IgG1抗体，该抗体识别与人类IgE类似的抗原决定簇，并抑制人类IgE-过敏原相互作用和过敏原诱导的嗜碱性粒细胞脱粒
4. Development of Single Domain Antibodies for Diagnosis and Treatment of Naturally Occurring Canine Lymphoma: An Animal Model for Human Non-Hodgkin Lymphoma [C] . Joana Dias, Solange Gil, Belmira Carrapico, PEGS . 2015

机译：天然犬淋巴瘤诊断和治疗单结构域抗体的发展：人非霍奇金淋巴瘤的动物模型
5. Do Dynamic Allosteric Effects Occur in IGG4 Antibodies? [D] . Baker, Lonnie Jonathan. 2020

机译：在IgG4抗体中发生动态变形效果吗？
6. Auto-anti-IgE: Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation [O] . Yih-Chih Chan, Faruk Ramadani, Alexandra F. Santos, -1

机译：自身抗IgE：天然存在的IgG抗IgE抗体可能抑制变应原诱导的嗜碱性粒细胞活化
7. "Auto-anti-IgE": Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation [O] . Chan, Yih-chih, Ramadani, Faruk, Santos, Alexandra F., 2014

机译：“自身抗IgE”：天然存在的IgG抗IgE抗体可能会抑制变应原诱导的嗜碱性粒细胞活化

'Auto-anti-IgE': Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation

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