Mercuric Triflate-TMU Catalyzed Hydration of Terminal Alkyne to give Methyl Ketone under Mild Conditions

摘要

Herein developed mercuric triflate-TMU catalyzed hydration of terminal alkyne is a mild procedure to give methyl ketone in excellent yield with high chemoselectivity. By using 0.05 eq of Hg(OTf)_2·(TMU)_2 and 3 eq of water, hydration takes place at a reasonable rate in acetonitrile.