Immunosuppressive effect of infectious bursal disease virus on immune response to ranikhet disease virus vaccine in chicks after F strain RD vaccination

摘要

Local IBD virus isolate proved immunosuppressive when given in 2-day-old WLH chicks and measured in terms of immune response to F-strain RD vaccine: Further the immunosuppressive effect was most marked when interval between experimental IBD virus infection and F-Strain vaccination was shortest while the efect was lowest when the interval was maximum. The age of the birds at the time of IBD virus infection, timing of RD vaccination and maternal antibody status to RD vaccine were some of the factors attributable for such effects.